UWCScholar :: Browsing by Author "Jeftha, Anthea"

Browsing by Author "Jeftha, Anthea"

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An evaluation of the outcomes of the surgical treatment of periodontitis at the University of the Western Cape, Tygerberg Oral Health Centre.
(University of the Western Cape, 2024) Abdalla, Mozn; Jeftha, Anthea
Background: Periodontal conditions are estimated to infect approximately 19% of the worldwide adult population, constituting more than one billion cases globally. Surgical periodontal therapy is recommended for treatment of deep pockets that are non-responsive to non-surgical periodontal therapy. While the overall treatment phases for periodontal disease are well documented in the literature, there remains significant uncertainty regarding the evidence to select the best options within these phases. Research is crucial to minimize this uncertainty and to compare various options for periodontal treatment outcomes. Aim: The study aimed to evaluate the clinical outcomes of surgical treatment of periodontitis carried out at the Periodontology Department of the University of the Western Cape, Tygerberg Oral Health Centre. Methods: A cohort record-based, retrospective analysis was carried out on 72 patients who underwent surgical periodontal therapy at Tygerberg Oral Health Centre between 2016 and 2022. Data was obtained from patients’ files and postgraduate students’ log books. The final treatment outcome of surgical periodontal procedures was analyzed by assessing and comparing pre- and post-surgical treatment periodontal parameters.
An assessment of the factors affecting the efficacy of periodontal treatment carried out by postgraduate periodontology students.
(University of Western Cape, 2020) Abdalla, Mozn; Jeftha, Anthea; Rayner, C.
Periodontal disease is one of the most common diseases worldwide. Periodontal treatment aims to prevent disease progression and restore functional and aesthetic dentition. The purpose of studying periodontal treatment outcome is to assess treatment efficacy. Treatment outcome of periodontal disease is affected by multiple patient-related factors, the type of treatment provided, and the expertise of the clinician.
The association of periodontal disease and metabolic control of type 1 adult patients with Diabetes at Tygerberg hospital, Cape Town
(University of the Western Cape, 2022) Suliman, Ahmed; Jeftha, Anthea
Periodontal disease is chronic inflammation of the periodontium. The inflammation can affect the gingival connective tissue or can progress, into the periodontal ligament and alveolar bone. Periodontal disease is a co-morbidity of diabetes and affects diabetics with poor control and suppressed immunity. This study compared the periodontal status of adults with Type 1 diabetes mellitus (T1DM) with their diabetic metabolic control. This cross-sectional study was conducted in adult patients diagnosed with T1DM. PD was assessed using the AAP as well as EFP 2017 classification. Periodontal parameters (bleeding index, periodontal pocket depth and radiographical bone loss) were assessed and the periodontal health of the diabetic patient was compared to their glycemic control.
The association of periodontal disease with metabolic control in type 1 diabetic adolescents
(University of Western Cape, 2020) Abdelrahman, Mohamed; Jeftha, Anthea; Conradie-Smit, Marli
Chronic inflammation of the periodontium is known as periodontal disease. The inflammation can be contained only within gingival connective tissue or can progress, leading to the loss of gingival connective tissue and alveolar bone. Lately, periodontal disease is considered as a co-morbidity of diabetes mellitus (Polak, Sanui et al., 2020). Though studies that have assessed the relationship of periodontal status with the glycemic control in type 1 diabetes mellitus adolescents, such studies have not been conducted in South Africa.
The comparison of periodontal health status and metabolic control in diabetic children and adolescents at Tygerberg hospital
(University of Western Cape, 2021) Scholtz-Evans, Lèzaan; Jeftha, Anthea
Diabetes Mellitus (DM) is a well-known risk factor for Periodontal disease. Research has established that the prevalence of Periodontal disease is directly related to the glycaemic control of DM in adults and only a few research studies explore this prevalence in diabetic children and adolescents in South Africa. The aim of this study is to determine the periodontal health status of diabetic patients which include children and adolescents attending the Paediatric Diabetic Clinic at Tygerberg Hospital and compare periodontal status with diabetic control. cross-sectional study was employed to determine periodontal status and data relating to the HbA1c% level, the type and duration of DM, the body mass index (BMI) percentile, age, sex, and puberty and treatment regimens were collected from patient records and entered into data collection sheets.
A description of dental implants placed at Tygerberg Oral Health Centre
(University of the Western Cape, 2019) Mahmoud, Hussein; Jeftha, Anthea
Purpose This study analyzed the dental surgical implant therapy in the past 5 years at Tygerberg Oral Health Centre, UWC Dental School, Cape Town, South Africa. The findings of this study serve as a guideline for the estimation of the prevalence in this dental hospital. The importance of this study was to aid in the establishment of the formalized electronic database for dental implant therapy. The data generated will form a foundational basis for future studies that may be conducted in the field of implantology. Methodology A retrospective cross-sectional study was conducted at the Tygerberg Oral Health Centre. The data was collected from the implant dental records for the years 2012-2017. Variables measured included the patient demographics such as age, gender, an implant placed by type, length, width, and anatomical location. Frequencies and means of data were generated using IBM SPSS v20.
A description of dental implants placed at Tygerberg Oral Health Centre
(University of Western Cape, 2020) Mahmoud, Hussein; Jeftha, Anthea; Gordon, Natalie
This study analyzed the dental surgical implant therapy in the past 5 years at Tygerberg Oral Health Centre, UWC Dental School, Cape Town, South Africa. The findings of this study serve as a guideline for the estimation of the prevalence in this dental hospital. The importance of this study was to aid in the establishment of the formalized electronic database for dental implant therapy. The data generated will form a foundational basis for future studies that may be conducted in the field of implantology.
A descriptive analysis of oral lichen planus from tertiary diagnostic centres in the Western Cape
(University of Western Cape, 2009) Jeftha, Anthea; Phillips, Vincent Michael
Lichen planus is a systemic disease that follows a chronic course. The exact aetiology remains unknown but an immune mediated pathogenesis has been implicated. Oral lichen planus is a common form of this disease and can occur in isolation or it may include the skin, genitalia and lesions involving the scalp and hair follicles. Epidemiological studies on oral lichen planus are few. Those that have been conducted have been in developed nations such as North America and Europe as well as Asia and the Middle East. Few African studies report on the demographics of the affected patients. Factors such as patient demographics and trends of diseases are essential to investigate. Findings of such studies may be useful in determining additional patient based criteria that can assist in obtaining a definitive diagnosis and subsequently aid in the management protocols of the specific disease in question. This process is as essential for oral lichen planus as for other diseases. Oral lichen planus can have clinical similarities with other diseases of the oral mucosa. Similarities can also be seen histologically that may further complicate the process of defining the diagnosis. Oral lichen planus may not be commonly associated with frank morbidity, but severe discomfort can be experienced in some clinical variants. This disease has been described as “difficult to manage” Camacho-Alonso et al, 2007). Furthermore, there is an ongoing debate about its malignant potential (Sugerman & Savage; 2002; Scully and Carrozzo; 2008). These factors support the relevance of further investigation of oral lichen planus. This study will report the demographics of patients who have been diagnosed with oral lichen planus in a subset of the South African population, within the Western Cape. The description of the ethnic groups in South Africa was as described by Statistics South Africa, namely; “African” was used to describe Black individuals, “Coloured” was used to describe individuals of mixed ethnic origin, “Indian” was used to describe patients whose ethnic origin was of the Indian/Asian continent, the latter however excluded persons of Chinese decent and “White” described those persons of European origin. The ethnic distribution reported from within the literature will report on the terminology used by the respective authors and hence not follow the guidelines outlined above.
Efficacy of alcohol containing and alcohol-free chlorhexidine mouth rinse in reducing periodontal disease during prophylactic treatment
(University of the Western Cape, 2018) Mpungose, Siphesihle P.; Jeftha, Anthea
Chlorhexidine has been established as the gold standard against which new chemical plaque control agents are tested (Jones, 1997). The addition of alcohol in a chlorhexidine mouthwash had been widely used, however the comparative efficacy of alcohol free chlorhexidine mouthwash had not fully been explored in this study, two chlorhexidine mouthwash preparations were tested to evaluate their comparative efficacy in the treatment of periodontal disease. Aims: To assess the efficacy of alcohol-free chlorhexidine mouth wash in comparison to alcohol containing chlorhexidine mouth wash. Objectives: To determine pre- and post- operative clinical parameters and microbial load in the management of patients with chronic periodontitis. Methodology: A double blinded randomised control trial was conducted. Patients diagnosed with active chronic periodontitis were included in the study and randomised to either a test (chlorhexidine without alcohol) or control group (chlorhexidine with alcohol). A total of 50 patients were selected for the study. Results: The Wilcoxon Signed Rank test was used to test the difference between the pre-post pair per clinical indicator and Bana-Zyme. The differences between before and after treatment per indicator were significant at P<0.001 for respectively Paroex and Peridex. These values demonstrated the difference between the clinical parameters taken before the treatment and six weeks post treatment. Conclusion: Both mouth wash solutions with and without alcohol had proven to reduce the microbial load as shown by the BANA-Zyme test, with the alcohol containing solution having been more effective.
Efficacy of gapseal® in preventing microleakage at the dental implant abutment interface
(University of Western Cape, 2021) Badi Mohamed, Hadeel Mohamed; Jeftha, Anthea; Maboza, Ernest
Dental implants have proven to be a success in the past decades, however the inevitable presence of microgaps at the implant abutment interface leading to microleakage is still a distressing concern. Microbial leakage can lead to peri-implant disease and bone loss and reduces implants' success rates. Measures to decrease the effect of the microgap were introduced; amongst them is the application of silicone sealing gels, such as GapSeal®.
Epidemiological pattern of oral squamous cell carcinoma seen at the Tygerberg academic complex
(University of the Western Cape, 2014) Hamid, Abdullahi Alhashimi; Jeftha, Anthea; Stephen, L.X.G.
Background: Recent epidemiological reports established that there is an increase in the incidence of oral squamous cell carcinoma in young patients. Some report this to be in the absence of contributing habits such as smoking and alcohol use. Few reports of such a nature have reported a similar trend in South Africa. Aim: Describe the epidemiological pattern of oral squamous cell carcinoma seen at the Tygerberg academic complex. Method: Histopathological biopsy reports of patients diagnosed by the oral pathology department of Tygerberg hospital from 1996 to 2013 were electronically retrieved and included. Patients were grouped by age into two groups, one included patients 40 years and younger, the other included patients older than 40 years. Descriptive analysis was performed for age, sex, smoking and alcohol habits and oral site of tumor. Frequency of OSCC patients was calculated manually from the total number of oral biopsies. Chi- square or Fisher’s exact tests were used as appropriate. Probabilities of less than 0.05 were regarded as significant. Results: The total number of OSCC patients over the 18-year period was 2220. The mean age was 57.6years.The male to female ratio was 2.9:1 for all age groups and 2.2:1 for young patients. The majority of patients (96%) were above 40 years old. Smoking and alcohol were commonly reported for all age groups (91.3%) and (83.8%) for young patients. The tongue was the commonest site for all age groups (30.8%) followed by oropharynx (27.3%) while in younger patients, the oropharynx was the commonest site (30.3%) followed by tongue (29.2%). Conclusion: The study confirmed that OSCC is still an affliction of people older than 40 years and males are predominantly affected. Smoking and alcohol are strong risk factors for OSCC irrespective of patient's age. OSCC among people older than 40 years may have no great difference from the same disease affecting younger ones in terms of sex, oral habits and tumor site.
Oral medicine case book 46: squamous cell carcinoma of the tongue
(South African Dental Association (SADA), 2013) Stander, Suzette; Jeftha, Anthea; Dreyer, Wynand P.; Abdairahman, B.; Afrogheh, Amir
A 38-year-old-female presented at the Oral Medicine Clinic complaining of pain under her tongue that became worse during chewing, and radiated to her right ear. The pain started two months earlier and gradually increased in intensity. The patient reported that she smoked about twelve cigarettes per day, a habit that she maintained for the last twenty years. She also admitted that she consumed alcohol as a social habit, mainly over the weekends. Her medical history revealed no other abnormalities and she was not using any chronic medication.
Oral medicine case book 47: oral neurofibroma
(South African Dental Association (SADA), 2013) Stander, Suzette; Dreyer, Wynand P.; Holmes, Haly; Jeftha, Anthea; Afrogheh, Amir
A 29-year-old male patient presented at the Oral Medicine Clinic with the complaint of slow-growing growths on his tongue, causing discomfort. Extra-oral examination revealed several painless soft tissue nodules on his face (Figure 1 and 2), trunk (Figure 3), back (Figure 4) and arms. The patient reported that the lesions had appeared during childhood and had since increased in size and number. He was unaware of any family history of the disease. Intra-oral examination showed two soft tissue nodules on the midline of the dorsal surface of the tongue, 3,5cm and 0,5 cm in diameter respectively (Figure 5).
Oral medicine case book 67: Oral manifestations of Evans syndrome: a presenting feature of HIV infection?
(South African Dental Association, 2015) Ranchod, S.; Jeftha, Anthea; Meyer, M.; Dreyer, Wynand P.;
A 19 year old female presented with spontaneous intra - oral bleeding of two days duration. The patient reported that she was, until recently, in good general health and also that she had an uncomplicated parturition three years ago. She recently started noticing blood in her stools and felt increasingly lethargic. There was no history of trauma or intra-oral intervention that may have initiated the bleeding. The clinical examination revealed marked pallor of the facial skin and multiple small petechiae were seen on both of her forearms. The intra-oral examination identified marked halitosis and multiple haemorrhagic lesions with a variable appearance, being plaque-like on the lip, nodular on the tongue and fungating and exophytic on the palate and in the retromolar regions. Even delicate manipulation of the tissues produced profuse bleeding.
Oral physiological pigmentation in a Western Cape sample
(University of the Western Cape, 2018) Govender, Shogan; Jeftha, Anthea
Oral physiological pigmentation presents with great variability with respect to sites, forms, patterns and contrasts in colour. Knowledge of the existence of pigmented lesions and their significance remained unclear for both the general public and oral clinicians alike. The possibility of malignant transformation of some pigmented lesions makes them important to monitor and biopsy. The prevalence of physiological pigmentation is unknown for the defined population group in this study. The results will be beneficial as part of a larger multicentre study with South Africa (Feller et al, 2015). Methodology: A cross sectional analytical study of patients that attended the University of the Western Cape Oral Health centres for routine treatment was conducted. After obtaining informed consent, patients were screened and asked a series of questions using a standardized questionnaire. From these completed questionnaires a prevalence relating to oral physiological pigmentation was determined. Oral physiological pigmentation did not have a male or female predominance in this study population group, but was associated with increased age. Oral pigmentation seemed to be well represented after 18 years of age. Patients were not usually aware of the pigmented gingiva unless being made aware off it.
Periodontitis and cardiovascular disease
(South African Dental Association (SADA), 2013) Jeftha, Anthea; Holmes, Haly
Periodontal medicine has been studied and reviewed extensively since its introduction to the dental fraternity. The association of periodontal disease with and its effects on the cardiovascular system are amongst the many topics explored. A summary of the research into these associations and the possible mechanisms of any relationship is presented. Although a link between these two chronic inflammatory diseases is evident, the very heterogeneity of the relevant studies has not provided evidence sufficient to support an actual causal relationship. More stringent epidemiologic and intervention studies are required.

Browsing by Author "Jeftha, Anthea"

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