The formulation and evaluation of indomethacin tablets

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Date

1998

Authors

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Journal ISSN

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Publisher

University of the Western Cape

Abstract

The overall objective of this research is to attempt to produce, by direct compression, indomethacin tablets which have good dissolution characteristics and an improved bioavailability profile, when compared to the capsule formulations currently available. In order to use the direct compression method, the solubilized form of indomethacin should have good flow properties, as well as a small bulk volume for incorporation into reasonably sized tablets.

Description

Magister Pharmaceuticae - MPharm

Keywords

Indomethacin tablets, Bioavailability, Dissolution characteristics, Capsules, Direct compression method, Solubilized indomethacin, Flow properties

Citation