Identification of sub-clinical biomarkers that predict the risk of developing diabetic cardiomyopathy

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dc.contributor.advisorBenjeddou, Mongi
dc.contributor.authorNxele, Xolisa
dc.date.accessioned2022-08-12T10:19:42Z
dc.date.accessioned2024-05-09T08:19:16Z
dc.date.available2022-08-12T10:19:42Z
dc.date.available2024-05-09T08:19:16Z
dc.date.issued2022
dc.descriptionPhilosophiae Doctor - PhDen_US
dc.description.abstractCardiovascular disease (CVD) is the leading cause of death of people with obesity and type 2 diabetes (T2DM). According to a statistical report from the World Health Organization (WHO), approximately 17.9 million people die annually because of CVD and diabetic cardiomyopathy (DCM), a disease of the heart muscle occurring in the absence of coronary artery disease or hypertension. Although not fully elucidated, the pathophysiology of DCM includes myocardial left ventricular hypertrophy, impaired calcium handling, energy metabolism, inflammation, apoptosis and myocardial fibrosis.en_US
dc.identifier.urihttps://hdl.handle.net/10566/13513
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectDiabetesen_US
dc.subjectCardiovascular diseaseen_US
dc.subjectHeart diseaseen_US
dc.subjectObesityen_US
dc.subjectBiotechnologyen_US
dc.titleIdentification of sub-clinical biomarkers that predict the risk of developing diabetic cardiomyopathyen_US

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