Browsing by Author "de Villiers, Carl"

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    Effect of non-surgical periodontal therapy on the anaemic status of patients with periodontitis: A systematic review
    (University of the Western Cape, 2024) de Villiers, Carl; Holmes, Haly
    Periodontitis is a chronic inflammatory disease resulting in progressive destruction of the tissues supporting the teeth (Hajishengallis and Chavakis, 2021). There is ever increasing evidence in the literature of the link between periodontitis and systemic diseases. The periodontal disease phenotype is characterised by an exaggerated, ineffective, and persistent inflammation of the connective tissues that supports the teeth, which ultimately results in tissue destruction and CAL (Meyle and Chapple, 2015). The main goal of periodontal treatment is to establish acceptable infection control by reducing the microbial load below individual threshold levels of inflammation (Suvan et al., 2020). Anaemia is a worldwide health problem that affects both the developed and developing world with far ranging effects on health of people including socio-economic burdens (Domenica Cappellini and Motta, 2015). Anaemia of chronic disease (ACD) is also known as anaemia of inflammation. Globally, this is the second most prevalent form of anaemia. ACD is usually mild, and the focus should be management of the underlying condition.
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    Oral manifestations of syphilis: Report of four cases
    (MDPI, 2022) van Staden, Suné Mulder; de Villiers, Carl; Alwan, Julandi
    Syphilis is an infectious disease caused by Treponema pallidum. Syphilis can present with an array of oral manifestations at different stages of disease progression. This article reports on four cases of syphilis with oral manifestations diagnosed by oral health professionals. Case 1: 18-year-old female presented with multiple ulcerations and patches involving the hard palate, uvula, retromolar area, and papillary nodules on the tongue. Case 2: 25-year-old male presented with a solitary, exophytic lesion on the anterior tongue. Case 3: 17-year-old female presented with multiple pigmented macules on the palms of hands and soles of feet, as well as multiple exophytic, sessile, soft tissue masses throughout the oral cavity. Case 4: 14-year-old female presented with a solitary, exophytic, verrucous lesion in the incisive papilla area, as well as multiple, coalescing patches involving the soft palate, uvula, and tonsillar areas. All patients were managed by biopsy and serological investigations.