Oral manifestations of syphilis: Report of four cases
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Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
MDPI
Abstract
Syphilis is an infectious disease caused by Treponema pallidum. Syphilis can present with
an array of oral manifestations at different stages of disease progression. This article reports on
four cases of syphilis with oral manifestations diagnosed by oral health professionals. Case 1:
18-year-old female presented with multiple ulcerations and patches involving the hard palate, uvula,
retromolar area, and papillary nodules on the tongue. Case 2: 25-year-old male presented with
a solitary, exophytic lesion on the anterior tongue. Case 3: 17-year-old female presented with
multiple pigmented macules on the palms of hands and soles of feet, as well as multiple exophytic,
sessile, soft tissue masses throughout the oral cavity. Case 4: 14-year-old female presented with
a solitary, exophytic, verrucous lesion in the incisive papilla area, as well as multiple, coalescing
patches involving the soft palate, uvula, and tonsillar areas. All patients were managed by biopsy
and serological investigations.
Description
Keywords
Oral lesions, Sexually Transmitted Infections, Oral health, Syphilis, Treponema pallidum
Citation
van Staden, S. M. et al. (2022). Oral manifestations of syphilis: Report of four cases. Pathogens , 11(6), 612. https://doi.org/10.3390/pathogens11060612