This study explored the impact of socio-demographic changes on informal sector employment in South Africa from 2017 to 2020. Utilizing data from the Quarterly Labour Force Survey (QLFS), descriptive statistics and logistic regression were employed to analyze relationships between age, gender, ethnicity, marital status, and education within the informal workforce. The results revealed significant shifts in employment patterns, particularly affecting youth and marginalized groups. The findings emphasize the vital role of socio-demographic factors in shaping the informal sector and highlight the need for targeted policies to support vulnerable populations and improve their economic opportunities in a fluctuating labor market.