An evaluation of the Bronchodilator properties of Mentha longifolia and Artemisia afra, traditional medicinal plants used in the Western Cape.

dc.contributor.advisorSyce, James
dc.contributor.authorHarris, Lynne
dc.date.accessioned2023-03-07T11:17:10Z
dc.date.accessioned2024-05-15T07:42:43Z
dc.date.available2023-03-07T11:17:10Z
dc.date.available2024-05-15T07:42:43Z
dc.date.issued2002
dc.descriptionMagister Pharmaceuticae - MPharmen_US
dc.description.abstractThe overall objective of this study was to investigate the claims that Mentha longifulia (ML) and Artemisia afra (AA) have anti-asthmatic properties. To realize this objective we were to determine the effects that the plants may have on contractions induced by agonists (e.g. methacholine, histamine, and leukotriene D+) and also to partially investigate the mechanism that may be involved' We hypothesized that extracts of Mentha longifotia arrd Artemisia afra would have respiratory airway smooth muscle relaxant properties and would be able to reverse methacholine and/or,histamine and/or leukotriene D+-induced contractions. plants were collected from Kirstenbosch National Botanical Institute and aqueous extracts prepared. Solutions of plant extracts were injected into an organ bath containing a zigzagcut guinea pig tracheal strip that had been pre-contracted with methacholine, histamine or leukotriene D+.en_US
dc.identifier.urihttps://hdl.handle.net/10566/15126
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectMentha longifoliaen_US
dc.subjectArtemisia afraen_US
dc.subjectPlantsen_US
dc.subjectMethacholineen_US
dc.subjectAsthmaen_US
dc.titleAn evaluation of the Bronchodilator properties of Mentha longifolia and Artemisia afra, traditional medicinal plants used in the Western Cape.en_US

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