Adult medical emergency unit presentations due to adverse drug reactions in a setting of high HIV prevalence
| dc.contributor.author | Igumbor, E | |
| dc.contributor.author | Mouton, J.P | |
| dc.contributor.author | Jobanputra, N | |
| dc.date.accessioned | 2021-05-11T12:45:36Z | |
| dc.date.available | 2021-05-11T12:45:36Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | South Africa has the world's largest antiretroviral treatment programme, which may contribute to the adverse drug reaction (ADR) burden. We aimed to determine the proportion of adult non-trauma emergency unit (EU) presentations attributable to ADRs and to characterise ADR-related EU presentations, stratified according to HIV status, to determine the contribution of drugs used in management of HIV and its complications to ADR-related EU presentations, and identify factors associated with ADR-related EU presentation. Methods: We conducted a retrospective folder review on a random 1.7% sample of presentations over a 12-month period in 2014/2015 to the EUs of two hospitals in Cape Town, South Africa. We identified potential ADRs with the help of a trigger tool. A multidisciplinary panel assessed potential ADRs for causality, severity, and preventability. | en_US |
| dc.identifier.citation | Igumbor, E. et al. (2021). Adult medical emergency unit presentations due to adverse drug reactions in a setting of high HIV prevalence. African Journal of Emergency Medicine ,11(1), 46-52 | en_US |
| dc.identifier.issn | 2211-419X | |
| dc.identifier.uri | 10.1016/j.afjem.2020.10.010 | |
| dc.identifier.uri | http://hdl.handle.net/10566/6145 | |
| dc.language.iso | en | en_US |
| dc.publisher | African Federation for Emergency Medicine | en_US |
| dc.subject | Adverse drug reaction | en_US |
| dc.subject | Emergency department | en_US |
| dc.subject | HIV | en_US |
| dc.subject | Prevalence | en_US |
| dc.subject | South Africa | en_US |
| dc.title | Adult medical emergency unit presentations due to adverse drug reactions in a setting of high HIV prevalence | en_US |
| dc.type | Article | en_US |