Engineering saccharomyces cerevisiae for application in integrated bioprocessing biorefineries
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Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier Ltd
Abstract
After decades of research and development, no organism — natural or engineered — has been described that can produce commodity products through direct microbial conversion to meet industry demands in terms of rates and yields. Variation in lignocellulosic biomass (LCB) feedstocks, the lack of a widely applicable pretreatment method, and the limited economic value of energy products further complicates second-generation biofuel production. Nevertheless, the emergence of advanced genomic editing tools and a more comprehensive understanding of yeast metabolic systems offer promising avenues for the creation of yeast strains tailored to LCB biorefineries. Here, we discuss recent advances toward developing yeast strains that could convert different LCB fractions into a series of economically viable commodity products in a biorefinery.
Description
Keywords
Commodity products, Biomass feedstock, Pretreatment methods, Economic values, Research and development
Citation
Minnaar, L.S., Kruger, F., Fortuin, J., Hoffmeester, L.J. and den Haan, R., 2024. Engineering Saccharomyces cerevisiae for application in integrated bioprocessing biorefineries. Current Opinion in Biotechnology, 85, p.103030.