Investigation of distinct gene expression profile patterns that can improve the classification of intermediate-risk prognosis in AML patients
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Date
2023
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Frontiers In Genetics
Abstract
Acute myeloid leukemia (AML) is a heterogeneous type of blood cancer that generally affects the elderly. AML patients are categorized with favorable-, intermediate-, and adverse risks based on an individual’s genomic features and chromosomal abnormalities. Despite the risk stratification, the progression and outcome of the disease remain highly variable. To facilitate and improve the risk stratification of AML patients, the study focused on gene expression profiling of AML patients within various risk categories.
Description
Keywords
acute myeloid leukemia, risk classification, intermediate-risk, gene expression, prognosis
Citation
Eshibona, N., Livesey, M. and Christoffels, A., 2023. Investigation of distinct gene expression profile patterns that can improve the classification of intermediate-risk prognosis in AML patients.