The prevalence of human papillomavirus–positive oropharyngeal squamous cell carcinoma at one of the largest tertiary care centers in Sub-Saharan Africa

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Date

2022

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College of American Pathologists

Abstract

Limited data exist on the prevalence of human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma in sub-Saharan Africa. OBJECTIVE.—: To determine the prevalence of HPV-positive oropharyngeal squamous cell carcinoma at a large tertiary care center in South Africa.A total of 266 oropharyngeal squamous cell carcinomas diagnosed during an 11-year period (2007-2017) were selected for evaluation. Cases staining positive for p16 immunohistochemistry were evaluated for high-risk HPV using the BD Onclarity assay (BD Diagnostics, Sparks, Maryland).

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Keywords

Human papillomavirus, Oropharyngeal neoplasms, Carcinoma, Squamous cell, Sub-Saharan Africa

Citation

Dapaah, G. et al. (2022). The prevalence of human papillomavirus–positive oropharyngeal squamous cell carcinoma at one of the largest tertiary care centers in Sub-Saharan Africa. Archives of pathology & laboratory medicine, 146(8), 1018-1023. https://doi.org/10.5858/arpa.2021-0021-OA

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https://doi.org/10.5858/arpa.2021-0021-OA
 http://hdl.handle.net/10566/7736

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