Antimicrobial efficacy of silver nanoparticles against candida albicans
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Date
2022
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
MDPI
Abstract
Current treatment protocols for patients diagnosed with denture stomatitis are under
scrutiny, and alternative options are being explored by researchers. The aim of this systematic review
was to determine if silver nanoparticles inhibit the growth of Candida albicans, and the research
question addressed was: In adults, do silver nanoparticles inhibit the growth of Candida albicans in acrylic
dentures and denture liners compared to normal treatment options. A systematic review was the chosen
methodology, and criteria were formulated to include all types of studies, including clinical and
laboratory designs where the aim was tested. Of the 18 included studies, only one was a clinical trial,
and 17 were in vitro research. The inhibition of candidal growth was based on the % concentration of
AgNPs included within the denture acrylic and denture liner. As the % AgNPs increased, candida
growth was reduced. This was reported as a reduction of candidal colony forming units in the studies.
The quality of the included studies was mostly acceptable, as seen from the structured and validated
assessments completed.
Description
Keywords
Denture stomatitis, Candida albicans, Silver nanoparticles, Denture liners, Oral candidiasis
Citation
Adam, R. Z., & Khan, S. B. (2022). Antimicrobial efficacy of silver nanoparticles against candida albicans. Materials, 15(16), 5666. https://doi.org/10.3390/ma15165666