Inter-individual genetic variation and the development of hypertension in a Xhosa African population of Eastern Cape, South Africa

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dc.contributor.advisorBenjeddou, Mongi
dc.contributor.authorMabhida, Sihle Ephraim
dc.date.accessioned2022-11-15T08:32:25Z
dc.date.accessioned2024-05-09T08:19:09Z
dc.date.available2024-05-09T08:19:09Z
dc.date.issued2022
dc.descriptionPhilosophiae Doctor - PhDen_US
dc.description.abstractCardiovascular diseases (CVD) are the leading cause of death globally, accounting for 18.6 million deaths. Hypertension (HTN) drives the global burden of CVD and is a leading cause of cardiovascular-related mortality with 1.4 billion affected adults and 10.4 million deaths globally. This public health condition has been escalating alarmingly in low and middle-income countries. In Sub-Saharan Africa, HTN is a major public health concern with South Africa having the highest prevalence between 27-58%. Accumulative evidence shows that HTN is driven by both modifiable and non-modifiable risk factors.en_US
dc.description.embargo2023
dc.identifier.urihttps://hdl.handle.net/10566/13480
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectAfrican populationen_US
dc.subjectGenesen_US
dc.subjectPharmacogenomicsen_US
dc.subjectBiotechnologyen_US
dc.subjectSouth Africaen_US
dc.titleInter-individual genetic variation and the development of hypertension in a Xhosa African population of Eastern Cape, South Africaen_US

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