Comparative study of the antioxidant constituents, activities and the gc-ms quantification and identification of fatty acids of four selected helichrysum species

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dc.contributor.authorAkinyede, Kolajo Adedamola
dc.contributor.authorHughes, Gail Denise
dc.contributor.authorEkpo, Okobi Eko
dc.date.accessioned2022-07-14T09:35:31Z
dc.date.available2022-07-14T09:35:31Z
dc.date.issued2022
dc.description.abstractHelichrysum Mill. (Asteraceae) is a plant genus comprising distinctively of aromatic plants of about 500–600 species. Since most of these plants have not been previously studied, extensive profiling helps to validate their folkloric uses and determine their potential value as sources of plantderived drug candidates. This study, therefore, aims to investigate the antioxidant activity (DPPH, NO, FRAP); total antioxidant capacity, total phenolic, total flavonoid, and fatty acid compositions of the aqueous acetone extracts from four Helichrysum plants namely, Helichrysum pandurifolium, Helichrysum foetidum, Helichrysum petiolare, and Helichrysum cymocum. The results obtained showed that the H. cymocum extract had the best DPPH radical scavenging activity (IC50 = 11.85 ± 3.20 µg/mL) and H. petiolare extract had the best nitric oxide scavenging activity (IC50 = 20.81 ± 3.73 µg/mL), while H. pandurifolium Schrank extract (0.636 ± 0.005 µg/mL) demonstrated the best ferrous reducing power, all of which are comparable with results from ascorbic acid used as the standard. The IC50 values of the radical scavenging activity ranged from 11.85–41.13 µg/mL (DPPH), 20.81–36.19 µg/mL (NO), and 0.505–0.636 µg/mL (FRAP), for all the plants studied. The H. petiolare has the highest total antioxidant capacity (48.50 ± 1.55 mg/g), highest total phenolic content (54.69 ± 0.23 mg/g), and highest total flavonoid content (56.19 ± 1.01 mg/g) compared with other species.en_US
dc.identifier.citationAkinyede, K. A. et al. (2022). Comparative study of the antioxidant constituents, activities and the gc-ms quantification and identification of fatty acids of four selected helichrysum species. Plants , 11(8), 998. https://doi.org/10.3390/plants11080998en_US
dc.identifier.issn2223-7747
dc.identifier.urihttps://doi.org/10.3390/plants11080998
dc.identifier.urihttp://hdl.handle.net/10566/7596
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.subjectAcidsen_US
dc.subjectDrugsen_US
dc.subjectHelichrysumen_US
dc.subjectBioscienceen_US
dc.subjectPlanten_US
dc.titleComparative study of the antioxidant constituents, activities and the gc-ms quantification and identification of fatty acids of four selected helichrysum speciesen_US
dc.typeArticleen_US

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