Hyphenated LC-ICP-MS/ESI-MS identification of halogenated metabolites in South African marine ascidian extracts

Simple item page
dc.contributor.authorBromley, Candice L.
dc.contributor.authorRaab, Andrea
dc.contributor.authorParker-Nance, Shirley
dc.contributor.authorBeukes, Denzil R.
dc.contributor.authorJaspars, Marcel
dc.contributor.authorDavies-Coleman, Michael T.
dc.date.accessioned2018-09-25T09:19:10Z
dc.date.available2018-09-25T09:19:10Z
dc.date.issued2018
dc.description.abstractExtracts of 13 species of marine ascidian collected in Algoa Bay were analyzed by LC-ICP-MS/ESI-MS. This technique allows parallel analysis of the molecular species and the presence of certain elements. The LC-ICP-MS/ESI-MS technique was used to target iodinated metabolites in this study. Three ascidian species afforded the known 3,5–diiodo-4-methoxyphenethylamine (12), which was confirmedby the isolation of this metabolite fromAplidium monile.MS also suggested the presence of theknown 3,5–dibromo-4-methoxyphenethylamine (10) and the new 3-bromo-5–iodo-4-methoxyphenethylamine (11) in the A. monile extract. The presence of the known 3,5-dibromotetramethyltyrosine (21) and the new 3-iodotetramethyltyrosine (23) in extracts of an unidentified Didemnum species was similarly proposed from MS evidence. This is the first report of the occurrence of iodinated metabolites in South African marine invertebrates.en_US
dc.description.accreditationISI
dc.identifier.citationBromley, C.L. et al. (2018). Hyphenated LC-ICP-MS/ESI-MS identification of halogenated metabolites in South African marine ascidian extracts. South African Journal of Chemistry, 71: 111–117.en_US
dc.identifier.issn1996-840X
dc.identifier.urihttp://dx.doi.org/10.17159/0379-4350/2018/v71a14
dc.identifier.urihttp://hdl.handle.net/10566/4076
dc.language.isoenen_US
dc.privacy.showsubmitterFALSE
dc.publisherThe South African Chemical Instituteen_US
dc.rightsAll the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
dc.status.ispeerreviewedTRUE
dc.subjectMarineen_US
dc.subjectAscidianen_US
dc.subjectIodinated tyramineen_US
dc.subjectIodinated tyrosineen_US
dc.subjectLC-ICP-MS/ESI-MSen_US
dc.titleHyphenated LC-ICP-MS/ESI-MS identification of halogenated metabolites in South African marine ascidian extractsen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Bromley_Hyphenated_2018.pdf
Size:
2.86 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Research Articles (Chemistry)