Hyphenated LC-ICP-MS/ESI-MS identification of halogenated metabolites in South African marine ascidian extracts
Loading...
Date
2018
Journal Title
Journal ISSN
Volume Title
Publisher
The South African Chemical Institute
Abstract
Extracts of 13 species of marine ascidian collected in Algoa Bay were analyzed by LC-ICP-MS/ESI-MS. This technique allows
parallel analysis of the molecular species and the presence of certain elements. The LC-ICP-MS/ESI-MS technique was used to
target iodinated metabolites in this study. Three ascidian species afforded the known 3,5–diiodo-4-methoxyphenethylamine
(12), which was confirmedby the isolation of this metabolite fromAplidium monile.MS also suggested the presence of theknown
3,5–dibromo-4-methoxyphenethylamine (10) and the new 3-bromo-5–iodo-4-methoxyphenethylamine (11) in the A. monile
extract. The presence of the known 3,5-dibromotetramethyltyrosine (21) and the new 3-iodotetramethyltyrosine (23) in extracts
of an unidentified Didemnum species was similarly proposed from MS evidence. This is the first report of the occurrence of
iodinated metabolites in South African marine invertebrates.
Description
Keywords
Marine, Ascidian, Iodinated tyramine, Iodinated tyrosine, LC-ICP-MS/ESI-MS
Citation
Bromley, C.L. et al. (2018). Hyphenated LC-ICP-MS/ESI-MS identification of halogenated metabolites in South African marine ascidian extracts. South African Journal of Chemistry, 71: 111–117.