Quantum dot nanotoxicity investigations using human lung cells and toxor electrochemical enzyme assay methodology

Simple item page
dc.contributor.authorO’Hara, Tony
dc.contributor.authorSeddon, Brian
dc.contributor.authorIwuoha, Emmanuel
dc.date.accessioned2023-06-06T09:14:17Z
dc.date.available2023-06-06T09:14:17Z
dc.date.issued2017
dc.description.abstractRecent studies have suggested that certain nanomaterials can interfere with optically based cytotoxicity assays resulting in underestimations of nanomaterial toxicity. As a result there has been growing interest in the use of whole cell electrochemical biosensors for nanotoxicity applications. Herein we report application of an electrochemical cytotoxicity assay developed in house (TOXOR) in the evaluation of toxic effects of mercaptosuccinic acid capped cadmium telluride quantum dots (MSA capped CdTe QDs), toward mammalian cells. MSA capped CdTe QDs were synthesized, characterized, and their cytotoxicity toward A549 human lung epithelial cells investigated. The internalization of QDs within cells was scrutinized via confocal microscopy.en_US
dc.identifier.citationO’Hara, T. et al. (2017). Quantum dot nanotoxicity investigations using human lung cells and toxor electrochemical enzyme assay methodology. ACS Sensors, 2 (1) ,165-171. https://doi.org/10.1021/acssensors.6b00673en_US
dc.identifier.issn2379-3694
dc.identifier.urihttps://doi.org/10.1021/acssensors.6b00673
dc.identifier.urihttp://hdl.handle.net/10566/9030
dc.language.isoenen_US
dc.publisherAmerican Chemical Societyen_US
dc.subjectChemistryen_US
dc.subjectElectrochemicalen_US
dc.subjectBiosensorsen_US
dc.subjectNanotoxicityen_US
dc.subjectPharmaceuticalsen_US
dc.titleQuantum dot nanotoxicity investigations using human lung cells and toxor electrochemical enzyme assay methodologyen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
o'hara_quatum dot nanotoxicity investigations_2017.pdf
Size:
2.89 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Research Articles (Chemistry)