Ultra-processed foods and mortality: Analysis from the prospective urban and rural epidemiology study

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Date

2022

Journal Title

Journal ISSN

Volume Title

Publisher

Oxford University Press

Abstract

This analysis includes 138,076 participants without a history of CVD between the ages of 35 and 70 y living on 5 continents, with a median follow-up of 10.2 y. We used country-specific validated food-frequency questionnaires to determine individuals’ food intake. We classified foods and beverages based on the NOVA classification into UPFs. The primary outcome was total mortality (CV and non-CV mortality) and secondary outcomes were incident major cardiovascular events. We calculated hazard ratios using multivariable Cox frailty models and evaluated the association of UPFs with total mortality, CV mortality, non-CV mortality, and major CVD events.

Description

Keywords

Food security, Mortality, Cardiovascular disease, Epidemiology

Citation

Dehghan, M., Mente, A., Rangarajan, S., Mohan, V., Swaminathan, S., Avezum, A., Lear, S.A., Rosengren, A., Poirier, P., Lanas, F. and Lopez-Jaramillo, P., 2023. Ultra-processed foods and mortality: analysis from the Prospective Urban and Rural Epidemiology study. The American journal of clinical nutrition, 117(1), pp.55-63.