The Internal Validation and Casework Application of MiniSTR Systems
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Date
2008
Authors
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Journal ISSN
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Publisher
University of the Western Cape
Abstract
The objective of the study was to conduct an internal validation on miniSTR systems and apply it to cases received from the South African Missing Persons Task Team (SAMPTT). This was prompted by the fact that miniSTR systems have been shown to out perform some of the commercial kits available in the time of the study and provide an alternative to mtDNA when analysing degraded DNA from skeletal remains and that the DNA extracted from skeletal remains received from the SAMPTT would be degraded due to the remains generally being fragmented or charred and buried for many years. The miniSTR loci chosen for validation comprised the Combined DNA Index System (CODIS) thirteen core loci and were arranged into four triplexes and one uniplex.
Description
Magister Scientiae - MSc
Keywords
Validation, MiniSTR, Short Tandem Repeat (STR), Loci, Y-STR, Political Violence, Degraded DNA