The Internal Validation and Casework Application of MiniSTR Systems

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dc.contributor.advisorLeat, Neil
dc.contributor.advisorDavison, Sean
dc.contributor.authorKleyn, Eugene Lyle
dc.contributor.otherDept. of Biotechnology
dc.contributor.otherFaculty of Science
dc.date.accessioned2013-11-21T18:11:51Z
dc.date.accessioned2024-05-09T07:45:01Z
dc.date.available2009/12/07 16:02
dc.date.available2009/12/07
dc.date.available2013-11-21T18:11:51Z
dc.date.available2024-05-09T07:45:01Z
dc.date.issued2008
dc.descriptionMagister Scientiae - MScen_US
dc.description.abstractThe objective of the study was to conduct an internal validation on miniSTR systems and apply it to cases received from the South African Missing Persons Task Team (SAMPTT). This was prompted by the fact that miniSTR systems have been shown to out perform some of the commercial kits available in the time of the study and provide an alternative to mtDNA when analysing degraded DNA from skeletal remains and that the DNA extracted from skeletal remains received from the SAMPTT would be degraded due to the remains generally being fragmented or charred and buried for many years. The miniSTR loci chosen for validation comprised the Combined DNA Index System (CODIS) thirteen core loci and were arranged into four triplexes and one uniplex.en_US
dc.description.countrySouth Africa
dc.identifier.urihttps://hdl.handle.net/10566/13269
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectValidationen_US
dc.subjectMiniSTRen_US
dc.subjectShort Tandem Repeat (STR)en_US
dc.subjectLocien_US
dc.subjectY-STRen_US
dc.subjectPolitical Violenceen_US
dc.subjectDegraded DNAen_US
dc.titleThe Internal Validation and Casework Application of MiniSTR Systemsen_US
dc.typeThesisen_US

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