Reconstruction of gene regulatory networks of inflammation-associated genes in different clinical stages of diffuse large B-cell lymphoma

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dc.contributor.advisorBendou, Hocine
dc.contributor.authorMfuphi, Nomlindelo Witness
dc.date.accessioned2022-10-28T12:59:15Z
dc.date.accessioned2024-05-17T07:20:04Z
dc.date.available2022-10-28T12:59:15Z
dc.date.available2024-05-17T07:20:04Z
dc.date.issued2022
dc.description>Magister Scientiae - MScen_US
dc.description.abstractDiffuse large B-cell lymphoma (DLBCL) is a heterogeneous malignancy that is driven by complex gene regulatory networks (GRNs). Numerous genes exert distinct effects on the progression and therapeutic outcome of DLBCL. Previous studies have associated DLBCL with inflammation but the GRNs involved in this mechanism have not yet been explored. The objectives of this current study are to reconstruct inflammation-associated networks and to understand the effects of inflammation on the pathogenesis and progression of DLBCL in different clinical stages.en_US
dc.identifier.urihttps://hdl.handle.net/10566/15223
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectBioinformaticsen_US
dc.subjectGene regulatory networksen_US
dc.subjectB-cell lymphomaen_US
dc.subjectGenesen_US
dc.titleReconstruction of gene regulatory networks of inflammation-associated genes in different clinical stages of diffuse large B-cell lymphomaen_US

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