Evaluation of the muscle relaxant orphenadrine in third molar surgery
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Date
2023
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Publisher
Universty of the Western Cape
Abstract
This clinical trial evaluates the efficacy of the muscle relaxant orphenadrine in reducing pain, swelling and trismus, and subsequent quality of life during the post-operative phase following third molar surgery. Forty patients requiring removal of impacted third molar teeth were included and randomly assigned to one of two treatment groups. One group received orphenadrine following surgery, while a control group received no muscle relaxant therapy. Surgical and anaesthetic techniques as well as post-operative pharmacological regimens were standardised. Wisdom teeth surgery has been shown to influence the quality of life of patients in the pre- and post-operative stages. In the post-operative stages, the quality of life may be influenced by the limitation in mouth opening that will directly influence daily functioning. The surgery is often performed in the operating room where intravenous drugs are administered and patients have all wisdom teeth removed at one visit; however, in certain circumstances it becomes challenging to take all wisdom teeth patients to the operating room, hence some will have to endure surgical removal under local anaesthesia. The aim of this study is to determine whether the use of muscle relaxants in the post-operative period will influence the quality of life of these patients. The literature reports on the use of corticosteroids perioperatively, but says little about the use of muscle relaxants.
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Keywords
Third molar, Muscle relaxant, Trismus, Impacted wisdom teeth, Orphenadrine