The beneficial role of anchomanes difformis in stz-induced reproductive dysfunction in male wistar rats
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Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
Dove Medical Press
Abstract
Progression of diabetes mellitus has increasingly led to several diabetic complications. Diabetes is one of the major factors implicated in male reproductive system damage. Recent approaches such as the use of medicinal plants have been explored in the management of diabetes and associated complications. Anchomanes difformis (common name: children’s umbrella) has been shown to possess anti-diabetic ability in animal model. Therefore, this study seeks to investigate the potency of Achomanes difformis in ameliorating diabetes-induced reproductive dysfunction. Methods: Type 2 diabetes was induced in male Wistar rats with 10% fructose administration for 2 weeks and an intraperitoneal injection of 40mg/kgBW of streptozotocin. Aqueous extract (200mg and 400mg/kgBW) of Anchomanes difformis leaves was administered daily for 6 weeks.
Description
Keywords
Anchomanes difformis, Diabetes mellitus, Male fertility, Sperm function, Male Wistar rats
Citation
Monsees, T. K. et al. (2020). The beneficial role of anchomanes difformis in stz-induced reproductive dysfunction in male wistar rats. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13, 4553-4560