The beneficial role of anchomanes difformis in stz-induced reproductive dysfunction in male wistar rats

dc.contributor.authorMonsees, Thomas K
dc.contributor.authorAlabi, Toyin Dorcas
dc.contributor.authorde Villiers, Charon
dc.date.accessioned2021-01-08T09:29:38Z
dc.date.available2021-01-08T09:29:38Z
dc.date.issued2020
dc.description.abstractProgression of diabetes mellitus has increasingly led to several diabetic complications. Diabetes is one of the major factors implicated in male reproductive system damage. Recent approaches such as the use of medicinal plants have been explored in the management of diabetes and associated complications. Anchomanes difformis (common name: children’s umbrella) has been shown to possess anti-diabetic ability in animal model. Therefore, this study seeks to investigate the potency of Achomanes difformis in ameliorating diabetes-induced reproductive dysfunction. Methods: Type 2 diabetes was induced in male Wistar rats with 10% fructose administration for 2 weeks and an intraperitoneal injection of 40mg/kgBW of streptozotocin. Aqueous extract (200mg and 400mg/kgBW) of Anchomanes difformis leaves was administered daily for 6 weeks.en_US
dc.identifier.citationMonsees, T. K. et al. (2020). The beneficial role of anchomanes difformis in stz-induced reproductive dysfunction in male wistar rats. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13, 4553-4560en_US
dc.identifier.issn1178-7007
dc.identifier.uri10.2147/DMSO.S270783
dc.identifier.urihttp://hdl.handle.net/10566/5618
dc.language.isoenen_US
dc.publisherDove Medical Pressen_US
dc.subjectAnchomanes difformisen_US
dc.subjectDiabetes mellitusen_US
dc.subjectMale fertilityen_US
dc.subjectSperm functionen_US
dc.subjectMale Wistar ratsen_US
dc.titleThe beneficial role of anchomanes difformis in stz-induced reproductive dysfunction in male wistar ratsen_US
dc.typeArticleen_US

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