A novel nano therapeutic using convalescent plasma derived exosomal (CPExo) for Covid-19: A combined hyperactive immune modulation and diagnostics

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dc.contributor.authorAnand, Krishnan
dc.contributor.authorVadivalagan, Chithravel
dc.contributor.authorShahbaaz, Mohd
dc.date.accessioned2022-07-19T07:37:19Z
dc.date.available2022-07-19T07:37:19Z
dc.date.issued2021
dc.description.abstractExtracellular vesicles like exosomes are important therapeutic tactics for treating COVID -19. By utilizing convalescent plasma derived exosomes (CPExo) from COVID-19 recovered persistence could accelerate the treatment strategies in the current state of affairs. Adequate literature has shown that administering the exosome to the in vivo system could be beneficial and could target the pathogens in an effective and precise manner. In this hypothesis we highlight the CPExo instead of convalescent plasma (CP), perhaps to dispense of exosomes are gratified and it’s more effectively acquired immune response conferral through antibodies. COVID-19 convalescent plasma has billions of exosomes and it has aptitudes to carry molecular constituents like proteins, lipids, RNA and DNA, etc. Moreover, exosomes are capable of recognizing antigens with adequate sensitivity and specificity. Many of these derivatives could trigger an immune modulation into the cells and act as an epigenetic inheritor response to target pathogens through RNAs. COIVID-19 resistance activated plasma-derived exosomes are either responsible for the effects of plasma beyond the contained immune antibodies or could be inhibitory.en_US
dc.identifier.citationAnand, K. et al. (2021). A novel nano therapeutic using convalescent plasma derived exosomal (CPExo) for Covid-19: A combined hyperactive immune modulation and diagnostics. Chemico-Biological Interactions, 344, 109497. 10.1016/j.cbi.2021.109497en_US
dc.identifier.issn0009-2797
dc.identifier.uri10.1016/j.cbi.2021.109497
dc.identifier.urihttp://hdl.handle.net/10566/7607
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectExosomesen_US
dc.subjectConvalescent plasmaen_US
dc.subjectImmunotherapyen_US
dc.subjectCovid-19en_US
dc.subjectDrugsen_US
dc.titleA novel nano therapeutic using convalescent plasma derived exosomal (CPExo) for Covid-19: A combined hyperactive immune modulation and diagnosticsen_US
dc.typeArticleen_US

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