Pharmaceutical evaluation of phela capsules Used as traditional medicine

dc.contributor.advisorSyce, James A.
dc.contributor.advisorMatsabisa, Gilbert Motlalepula
dc.contributor.authorSehume, Brian J.
dc.contributor.otherSchool of Pharmacy
dc.contributor.otherFaculty of Community and Health Sciences
dc.date.accessioned2013-09-03T13:54:56Z
dc.date.accessioned2024-05-15T07:43:09Z
dc.date.available2011/03/07 09:16
dc.date.available2011/03/07
dc.date.available2013-09-03T13:54:56Z
dc.date.available2024-05-15T07:43:09Z
dc.date.issued2010
dc.descriptionMagister Pharmaceuticae - MPharmen_US
dc.description.abstractIn conclusion, the results obtained firstly indicated that the BP, EMEA and WHO were in fairly good agreement on the criteria and specifications that can be used to assesses the pharmaceutical quality of a traditional plant medicine such as Phela. Secondly, the Phela plant powders were found to have acceptable pharmaceutical properties that did not complicate or adversely affected the capsule manufacture. Thirdly, the Phela capsules produced were generally of acceptable pharmacopoeial standard. Fourthly, HPLC fingerprinting and pattern recognition analysis proved useful to examine the chemical stability of selected marker compounds of Phela and indicated that the capsules had no practical shelf life under elevated temperature and humid conditions. Overall, the Phela capsules should thus be suitable for use in a short time clinical trial, but for use in a long period trial the long term stability of the Phela capsules under ambient conditions must still be confirmed.en_US
dc.description.countrySouth Africa
dc.identifier.urihttps://hdl.handle.net/10566/15196
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectPhelaen_US
dc.subjectHerbal capsulesen_US
dc.subjectTraditional medicineen_US
dc.subjectPharmaceutical evaluationen_US
dc.subjectDissolutionen_US
dc.subjectStability studiesen_US
dc.subjectHPLCen_US
dc.titlePharmaceutical evaluation of phela capsules Used as traditional medicineen_US
dc.typeThesisen_US

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