Transient transgene expression of human Coronavirus nl63 orf3 protein in a baculovirus system
| dc.contributor.advisor | Fielding, Burtram | |
| dc.contributor.author | Liedeman, Kerwin | |
| dc.date.accessioned | 2021-03-25T08:36:30Z | |
| dc.date.accessioned | 2024-11-04T13:14:59Z | |
| dc.date.available | 2021-03-25T08:36:30Z | |
| dc.date.available | 2024-11-04T13:14:59Z | |
| dc.date.issued | 2020 | |
| dc.description | Magister Scientiae (Medical Bioscience) - MSc(MBS) | en_US |
| dc.description.abstract | Insect-derived baculoviruses have been used extensively as a safe and versatile research model for transgenic protein expression. Preclinical studies have revealed the promising potential of Baculoviruses as a delivery vector for a variety of therapeutic applications, including vaccination, tissue engineering and cancer treatments. Coronaviruses are enveloped viruses containing linear, non-segmented ribonucleic acid. Human coronavirus NL63 was first discovered in the Netherlands in January 2004, where a 7-month-old girl presented with an acute respiratory tract infection that was later established to predominantly infect infants, the elderly and immunocompromised individuals. | en_US |
| dc.identifier.uri | https://hdl.handle.net/10566/17227 | |
| dc.language.iso | en | en_US |
| dc.publisher | University of Western Cape | en_US |
| dc.rights.holder | University of Western Cape | en_US |
| dc.subject | Human Coronavirus | en_US |
| dc.subject | Baculovirus system | en_US |
| dc.subject | Transgenic protein expression | en_US |
| dc.subject | Viruses | en_US |
| dc.subject | Bacterial cell lines | en_US |
| dc.title | Transient transgene expression of human Coronavirus nl63 orf3 protein in a baculovirus system | en_US |