Persistent pharmaceuticals in a South African urban estuary and bioaccumulation in endobenthic sandprawns (Kraussillichirus kraussi)

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Date

2025

Journal Title

Journal ISSN

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Publisher

Multidisciplinary Digital Publishing Institute (MDPI)

Abstract

Pharmaceuticals are increasingly being detected in coastal ecosystems globally, but contamination and bioaccumulation levels are understudied in temporarily closed estuaries. In these systems, limited freshwater inputs and periodic closure may predispose them to pharmaceutical accumulation. We quantified in situ water column pharmaceutical levels at five sites in a temporarily closed model urban estuary (Zandvlei Estuary) in Cape Town, South Africa, that has been heavily anthropogenically modified. The results indicate an almost 100-fold greater concentration of pharmaceuticals in the estuary relative to False Bay, into which the estuary discharges, with acetaminophen (max: 2.531 µg/L) and sulfamethoxazole (max: 0.138 µg/L) being the primary pollutants. Acetaminophen was potentially bioaccumulative, while nevirapine, carbamazepine and sulfamethoxazole were bioaccumulated (BAF > 5000 L/kg) by sandprawns (Kraussillichirus kraussi), which are key coastal endobenthic ecosystem engineers in southern Africa. The assimilative capacity of temporarily closed estuarine environments may be adversely impacted by wastewater discharges that contain diverse pharmaceuticals, based upon the high bioaccumulation detected in key benthic engineers.

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Keywords

antibiotics, bioaccumulation, ecosystem engineer, pollution, temporarily closed estuary

Citation

Murgatroyd, O., Petrik, L., Ojemaye, C.Y. and Pillay, D., 2025. Persistent Pharmaceuticals in a South African Urban Estuary and Bioaccumulation in Endobenthic Sandprawns (Kraussillichirus kraussi). Water, 17(15), p.2289.