The combat-tb workbench: Making powerful Mycobacterium tuberculosis bioinformatics accessible

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dc.contributor.authorvan Heusden, Peter
dc.contributor.authorMashologu, Ziphozakhe
dc.contributor.authorLose, Thoba
dc.date.accessioned2022-09-19T10:14:36Z
dc.date.available2022-09-19T10:14:36Z
dc.date.issued2022
dc.description.abstractWhole-genome sequencing (WGS) is a powerful method for detecting drug resistance, genetic diversity, and transmission dynamics of Mycobacterium tuberculosis. Implementation of WGS in public health microbiology laboratories is impeded by a lack of user-friendly, automated, and semiautomated pipelines. We present the COMBAT-TB Workbench, a modular, easy-to-install application that provides a web-based environment for Mycobacterium tuberculosis bioinformatics. The COMBAT-TB Workbench is built using two main software components: the IRIDA platform for its web-based user interface and data management capabilities and the Galaxy bioinformatics workflow platform for workflow execution.en_US
dc.identifier.citationvan Heusden, P. et al. (2022). The combat-tb workbench: Making powerful mycobacterium Tuberculosis bioinformatics accessible. mSphere, 7(1), e00991-21. https://doi.org/10.1128/msphere.00991-21en_US
dc.identifier.issn2379-5042
dc.identifier.urihttps://doi.org/10.1128/msphere.00991-21
dc.identifier.urihttp://hdl.handle.net/10566/7914
dc.language.isoenen_US
dc.publisherAmerican Society for Microbiologyen_US
dc.subjectMycobacterium tuberculosisen_US
dc.subjectBioinformaticsen_US
dc.subjectTuberculosisen_US
dc.subjectBiologyen_US
dc.titleThe combat-tb workbench: Making powerful Mycobacterium tuberculosis bioinformatics accessibleen_US
dc.typeArticleen_US

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