Genetic characterization of the central variable region in African swine fever virus isolates in the Russian federation from 2013 to 2017
Loading...
Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
MDPI
Abstract
African swine fever virus (ASFV), classified as genotype II, was introduced into Georgia in
2007, and from there, it spread quickly and extensively across the Caucasus to Russia, Europe and
Asia. The molecular epidemiology and evolution of these isolates are predominantly investigated by
means of phylogenetic analysis based on complete genome sequences. Since this is a costly and timeconsuming
endeavor, short genomic regions containing informative polymorphisms are pursued
and utilized instead. In this study, sequences of the central variable region (CVR) located within the
B602L gene were determined for 55 ASFV isolates submitted from 526 active African swine fever
(ASF) outbreaks occurring in 23 different regions across the Russian Federation (RF) between 2013
and 2017. The new sequences were compared to previously published data available from Genbank,
representing isolates from Europe and Asia. The sequences clustered into six distinct groups.
Description
Keywords
Swine fever virus, Africa, Public health, Biotechnology, Domestic pigs
Citation
Mazloum, A. et al. (2022). Genetic characterization of the central variable region in African swine fever virus isolates in the Russian federation from 2013 to 2017. Pathogens, 11(8), 919. https://doi.org/10.3390/pathogens11080919