Genetic characterization of the central variable region in African swine fever virus isolates in the Russian federation from 2013 to 2017

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dc.contributor.authorMazloum, Ali
dc.contributor.authorVan Schalkwyk, Antoinette
dc.contributor.authorChernyshev, Roman
dc.date.accessioned2022-09-19T07:22:27Z
dc.date.available2022-09-19T07:22:27Z
dc.date.issued2022
dc.description.abstractAfrican swine fever virus (ASFV), classified as genotype II, was introduced into Georgia in 2007, and from there, it spread quickly and extensively across the Caucasus to Russia, Europe and Asia. The molecular epidemiology and evolution of these isolates are predominantly investigated by means of phylogenetic analysis based on complete genome sequences. Since this is a costly and timeconsuming endeavor, short genomic regions containing informative polymorphisms are pursued and utilized instead. In this study, sequences of the central variable region (CVR) located within the B602L gene were determined for 55 ASFV isolates submitted from 526 active African swine fever (ASF) outbreaks occurring in 23 different regions across the Russian Federation (RF) between 2013 and 2017. The new sequences were compared to previously published data available from Genbank, representing isolates from Europe and Asia. The sequences clustered into six distinct groups.en_US
dc.identifier.citationMazloum, A. et al. (2022). Genetic characterization of the central variable region in African swine fever virus isolates in the Russian federation from 2013 to 2017. Pathogens, 11(8), 919. https://doi.org/10.3390/pathogens11080919en_US
dc.identifier.issn2076-0817
dc.identifier.urihttps://doi.org/10.3390/pathogens11080919
dc.identifier.urihttp://hdl.handle.net/10566/7903
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.subjectSwine fever virusen_US
dc.subjectAfricaen_US
dc.subjectPublic healthen_US
dc.subjectBiotechnologyen_US
dc.subjectDomestic pigsen_US
dc.titleGenetic characterization of the central variable region in African swine fever virus isolates in the Russian federation from 2013 to 2017en_US
dc.typeArticleen_US

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