The design and evaluation of ciprofloxacin-loaded nanoformulations using Ipomoea batatas starch nanoparticles

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dc.contributor.authorAjala, Tolulope O.
dc.contributor.authorOmoteso, Omobolanle A.
dc.contributor.authorAwe, Oladotun M.
dc.date.accessioned2023-06-05T12:13:58Z
dc.date.available2023-06-05T12:13:58Z
dc.date.issued2023
dc.description.abstractStarch nanoparticle derivatives are gaining popularity as drug delivery vehicles because of their biocompatibility, better mechanical characteristics, heat stability properties, impediment qualities, permeability capabilities, and flexibility to be changed for specific predetermined functions. The effect of techniques and processing time on the physiochemical and drug release characteristics of sweet potato (Ipomoea batatas) starch nanoparticles and their ciprofloxacin-loaded nanoformulations was studied. Scanning electron microscopy confirmed that the treated starch formed nanoparticles and also revealed significant changes in the morphology of the treated starches. The water absorption capacity of chemically treated starch nanoparticles (CTSN)-3 days was the highest, whereas CTSN-6 days had the maximum solubility. The functional groups present in the starch nanoparticles were confirmed by Fourier transform infrared spectroscopy and Raman. The thermal characteristics of starch nanoparticles were established using hot-stage microscopy, differential scanning calorimetry, and thermogravimetric analysis.en_US
dc.identifier.citationAjala, T. O. et al. (2023). The design and evaluation of ciprofloxacin-loaded nanoformulations using Ipomoea batatas starch nanoparticles. Future Journal of Pharmaceutical Sciences, 9, 37. https://doi.org/10.1186/s43094-023-00487-zen_US
dc.identifier.issn2314-7253
dc.identifier.urihttps://doi.org/10.1186/s43094-023-00487-z
dc.identifier.urihttp://hdl.handle.net/10566/9020
dc.language.isoenen_US
dc.publisherSpringerOpenen_US
dc.subjectPharmacologyen_US
dc.subjectStarch nanoparticleen_US
dc.subjectDrug release studiesen_US
dc.subjectNanotechnologyen_US
dc.subjectPhysiological chemistryen_US
dc.titleThe design and evaluation of ciprofloxacin-loaded nanoformulations using Ipomoea batatas starch nanoparticlesen_US
dc.typeArticleen_US

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