Identification and characterisation of a novel gene, DWNN, isolated from promoter-trapped Chinese hamster ovary cells
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Date
2005
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
University of the Western Cape
Abstract
The process of cytotoxic T lymphocyte (CTL) killing involves the recognition and destruction of foreign antigens by cytotoxic T cells and is of crucial importance to the defence of the organism against viral infections. Defects in this process can lead to various autoimmune diseases and cancer. The aim of this study was to identify more genes involved in the cell death pathway and to link CTL killing, apoptosis and cancer.
Description
Philosophiae Doctor - PhD
Keywords
Apoptosis, Cell death, Pathology, Cellular