The antimicrobial and antifungal efficacy of indigenous plant extracts against streptococcus mutans, Escherichia colia and Candida albicans

dc.contributor.advisorPeerbhay, Fatima
dc.contributor.advisorBasson, Nicolaas J
dc.contributor.authorElashi, Balsam
dc.date.accessioned2015-06-01T12:45:40Z
dc.date.accessioned2024-06-04T08:26:53Z
dc.date.available2015-06-01T12:45:40Z
dc.date.available2024-06-04T08:26:53Z
dc.date.issued2015
dc.descriptionMagister Scientiae Dentium - MSc(Dent)en_US
dc.description.abstractThe antimicrobial and antifungal efficacy of indigenous plant extracts against Streptococcus mutans , Escherichia coli and Candida albicans .Aim: To determine the antimicrobial and antifungal efficacy of indigenous plant extracts, Tamarindus Indica (T. ndica), Hibiscus sabdariffa (H. sabdaraffi), Adansonia digitata (A.digitata) and Moringa oleifera (M. oleifera) against Streptococcus mutans ( S. mutans ), Escherichia coli ( E. coli ) and Candida albicans (C. albicans) objectives:The objectives of this study were to: 1.Measure the zones of growth inhibition by T. indicia , A. digitata , M.oleifera and H. sabdariffi extracts against, S.mutans , E.coli and C.albicans . 2.Compare the size of inhibition zones of different bacteria or fungus, S. mutans ,E.coli and C. albicans, around the same plant extract.3.Compare the size of inhibition zones for the same bacteria in different plant extracts T.indicia ,A.digitata H.sabdariffi and M.oleifera Methodology .The antimicrobial and antifungal effect of the ethanolic extracts of T. indica , H.sabdariffa, A.digitata and M.oleifera was performed using the disc diffusion method against S. mutans ,E.coli and C.albicans. The antibacterial and antifungal activity of the plants was determined by measuring the diameter of the inhibition zones. esults and conclusion: The results showed that.T.indica and H.sabdariffa ethanolic extracts have an antibacterial effect against S.mutans and E.coli.However, H.sabdariffi showed a significantly higher antibacterial effect against E.coli and S.mutans, with a range of 14.50mm to 12.01mm and 16.41 mm to 14.39 mm compared to T.indica ,with a range of 11.41 mm to 7.04mm and 6.88mm to 10.40mm, respectively.Furthermore, the statistical multiple pairwise test (Conover Iman procedure/Two -tailed test) omputed that the effect of H.sabdariffi is significantly (critical value >7.229) greater for the G ram positive S.mutans than the G ram negative E.coli.On the other hand,T.indica showed a similar antibacterial effect against S.mutans and E.coli,respectively.In contrast, M. oleifera and A.digitata ethanolic plant extracts showed no antibacterial effect against E.coli and S.mutans. All the indigenous plants tested, T.indica ,H.sabdariffa, M. oleifera and A.digitata had no antifungal activity on C.albicansen_US
dc.identifier.urihttps://hdl.handle.net/10566/15832
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectStreptococcus mutansen_US
dc.subjectEscherichia colien_US
dc.subjectAntibacterialen_US
dc.subjectAntifungalen_US
dc.subjectHibiscus sabdariffaen_US
dc.subjectTraditional medicineen_US
dc.titleThe antimicrobial and antifungal efficacy of indigenous plant extracts against streptococcus mutans, Escherichia colia and Candida albicansen_US

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