Browsing by Author "van Zyl, Marjorie"
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Item The Coronavirus Nucleocapsid is a Multifunctional Protein(MDPI, 2014) McBride, Ruth; van Zyl, Marjorie; Fielding, Burtram C.The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus transcription and assembly. Recent studies have confirmed that N is a multifunctional protein. The aim of this review is to highlight the properties and functions of the N protein, with specific reference to (i) the topology; (ii) the intracellular localization and (iii) the functions of the protein.