Browsing by Author "Roberts, Tina Sharon"

Now showing 1 - 3 of 3
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    CHARGE syndrome: Genetic aspects and dental challenges, a review and case presentation
    (Springer Nature, 2020) Chetty, Manogari; Roberts, Tina Sharon; Elmubarak, Mona
    CHARGE syndrome (CS) is a rare genetic condition (OMIM #214800). The condition has a variable phenotypic expression. Historically, the diagnosis of CHARGE syndrome was based on the presence of specific clinical criteria. The genetic aetiology of CS has since been elucidated and attributed to pathogenic variation in the CHD7 gene (OMIM 608892) at chromosome locus 8q12.
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    An investigation into the role of histological parameters in the prediction of the prognosis for tl and t2 oral squamous cell carcinomas
    (University of Western Cape, 1998) Roberts, Tina Sharon; Hille, Josh
    TI and T2 squamous cell carcinomas of the head and neck have an unpredictable prognosis that often pose therapeutic problems. Sophisticated methods such as cytometric DNA analysis, immunocytochemistry and detection of cellular growth factors, have been applied with varying success rates for predicting recurrences, metastatic rates and overall prognoses. However, with the general lack of resources in Africa, devising a simple, reliable, reproducible and cost-effective method of predicting tumour behaviour to aid optimal treatment planning is imperative. Surgical excision specimens of forty-eight primary Tl and T2 squamous cell carcinomas of the floor of the mouth and tongue were histologically evaluated by two individual pathologists (double-blinded study) who had no prior knowledge of clinical course or outcome.
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    Sexual dimorphism in odontometric parameters using cone beam CT: A systematic review
    (BMC, 2023) Ajmal, M. A.; Roberts, Tina Sharon; Beshtawi, Khaled R.
    To determine whether odontometric parameters using cone beam computed tomography (CBCT) would aid in sex estimation by assessing sexual dimorphism of odontometric parameters. The focused question was whether there is sexual dimorphism in linear and volumetric odontometric parameters when assessed using CBCT. The preferred reporting items for systematic reviews and metaanalysis (PRISMA) guidelines were followed to conduct a systematic search until June 2022 in all major databases. Data were extracted regarding the population, size of the sample, age range, teeth analyzed, linear or volumetric measurements, accuracy, and conclusion. The quality of included studies was assessed using (Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool.