Browsing by Author "Nel, D. G."

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    The effects of in utero exposure to teratogens on organ size: A prospective paediatric study
    (Cambridge University Press, 2021) De Smidt, Juley; Odendaal, H. J.; Nel, D. G.
    In low-income countries, prospective data on combined effects of in utero teratogen exposure are lacking and necessitates new research. The aim of the present study was to explore the effect of in utero teratogen exposure on the size of the kidneys and pancreas 5 years after birth in a low-income paediatric population. Data was collected from 500 mother–child pairs from a lowincome setting. Anthropometric measurements included body weight, (BW) body height, midupper arm and waist circumference (WC). Clinical measurements included blood pressure (BP), mean arterial pressure and heart rate. Ultrasound measurements included pancreas, and kidney measurements at age 5 years. The main outcome of interest was the effect of maternal smoking and alcohol consumption on ultrasound measurements of organ size at age 5 years.