Browsing by Author "Lategan, Kim Leigh"

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    The stability and anti-angiogenic properties of titanium dioxide nanoparticles (tio2nps) using caco-2 cells
    (MDPI, 2022) David, Oladipupo Moyinoluwa; Lategan, Kim Leigh; de Cortalezzi, Maria Fidalgo
    Titanium dioxide nanoparticles (TiO2NPs) are found in a wide range of products such as sunscreen, paints, toothpaste and cosmetics due to their white pigment and high refractive index. These wide-ranging applications could result in direct or indirect exposure of these NPs to humans and the environment. Accordingly, conflicting levels of toxicity has been associated with these NPs. Therefore, the risk associated with these reports and for TiO2NPs produced using varying methodologies should be measured. This study aimed to investigate the effects of various media on TiO2NP properties (hydrodynamic size and zeta potential) and the effects of TiO2NP exposure on human colorectal adenocarcinoma (Caco-2) epithelial cell viability, inflammatory and cell stress biomarkers and angiogenesis proteome profiles.