The stability and anti-angiogenic properties of titanium dioxide nanoparticles (tio2nps) using caco-2 cells

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Date

2022

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MDPI

Abstract

Titanium dioxide nanoparticles (TiO2NPs) are found in a wide range of products such as sunscreen, paints, toothpaste and cosmetics due to their white pigment and high refractive index. These wide-ranging applications could result in direct or indirect exposure of these NPs to humans and the environment. Accordingly, conflicting levels of toxicity has been associated with these NPs. Therefore, the risk associated with these reports and for TiO2NPs produced using varying methodologies should be measured. This study aimed to investigate the effects of various media on TiO2NP properties (hydrodynamic size and zeta potential) and the effects of TiO2NP exposure on human colorectal adenocarcinoma (Caco-2) epithelial cell viability, inflammatory and cell stress biomarkers and angiogenesis proteome profiles.

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Keywords

Bioscience, Titanium dioxide, Nanoparticles, Angiogenesis, Biomolecules

Citation

David, O. M. et al. (2022). The stability and anti-angiogenic properties of titanium dioxide nanoparticles (tio2nps) using caco-2 cells. Biomolecules, 12(10), 1334. https://doi.org/10.3390/biom12101334

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https://doi.org/10.3390/biom12101334
 http://hdl.handle.net/10566/8119

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Research Articles (Medical Bioscience)