Browsing by Author "Elbagory, Abdulrahman Mohammed"

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    The antimicrobial and anti-inflammatory effects of silver nanoparticles synthesised from cotyledon orbiculata aqueous extract
    (MDPI, 2021) Tyavambiza, Caroline; Elbagory, Abdulrahman Mohammed; Madiehe, Abram Madimabe
    Cotyledon orbiculata, commonly known as pig’s ear, is an important medicinal plant of South Africa. It is used in traditional medicine to treat many ailments, including skin eruptions, abscesses, inflammation, boils and acne. Many plants have been used to synthesize metallic nanoparticles, particularly silver nanoparticles (AgNPs). However, the synthesis of AgNPs from C. orbiculata has never been reported before. The aim of this study was to synthesize AgNPs using C. orbiculata and evaluate their antimicrobial and immunomodulatory properties. AgNPs were synthesized and characterized using Ultraviolet-Visible Spectroscopy (UV-Vis), Dynamic Light Scattering (DLS) and High-Resolution Transmission Electron Microscopy (HR-TEM).
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    Chemical and biological evaluation of palythoa tuberculosa collected from the red sea
    (University of the Western Cape, 2015) Elbagory, Abdulrahman Mohammed; Mohammed, Ahmed; Meyer, Mervin
    A chemical study on the total extract of the zoanthid Palythoa tuberculosa, collected from the Red Sea, resulted in the isolation of seven polyhydroxylated sterols viz: palysterols A-G, six of which are new. Their chemical structures were elucidated on the basis of their 1D and 2D NMR and MS spectroscopic data. Palysterols B and G demonstrated cytotoxic activity on three human cancer cell lines (MCF-7, HeLa, and HT- 29). Palysterol G, in particular, was able to induce apoptosis in breast adenocarcinoma(MCF-7) cells