Browsing by Author "Ahmed, Omnia Abdelmoneim Khidir"

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    An in-vitro evaluation of the efficacy of oral devices to remove dental biofilm from three prosthodontic materials
    (University of the Western Cape, 2019) Ahmed, Omnia Abdelmoneim Khidir; Moodley, Desi
    Introduction: The evolution of Dentistry witnessed an increase in fixed prostheses as opposed to removable ones. Zirconia (ZrO2) and Lithium disilicate (LDS) are becoming the material of choice in implant or tooth retained prostheses. Polyetheretherketone (PEEK) is a recent alternative as it is lighter and causes less wear of opposing retained teeth. Biofilm formation is a permanent daily struggle for patients as it can be found in nearly all surfaces exposed to the natural environment. Therefore, the interest in a new device capable of removing or reducing oral biofilm from fixed prostheses is increasing. Aquaflosser (AQ) and Waterpik (WP) are examples of these oral irrigating devices that were introduced to the dental market recently. They can be effective in removing dental biofilm from different surfaces. Purpose of study: The purpose of this study is to evaluate biofilm formation on three fixed dental substructures and to evaluate the efficacy of two oral irrigating devices on biofilm removal from these three substructures.
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    Prospects of using gum Arabic silver nanoparticles in toothpaste to prevent dental caries
    (MDPI, 2023) Ahmed, Omnia Abdelmoneim Khidir; Sibuyi, Nicole Remaliah Samantha; Fadaka, Adewale Oluwaseun
    There is growing interest in the use of green synthesized silver nanoparticles (AgNPs) to control and prevent dental diseases. The incorporation of green synthesized AgNPs into dentifrices to reduce pathogenic oral microbes is motivated by their presumed biocompatibility and broad-spectrum antimicrobial activity. In the present study, gum arabic AgNPs (GA-AgNPs) were formulated into a toothpaste (TP) using a commercial TP at a non-active concentration, to produce GA-AgNPs_TP. The TP was selected after evaluating the antimicrobial activity of four commercial TPs 1-4 on selected oral microbes using agar disc diffusion and microdilution assays. The less active TP-1 was then used in the formulation of GA-AgNPs_TP-1; thereafter, the antimicrobial activity of GA-AgNPs_0.4g was compared to GA-AgNPs_TP-1. The cytotoxicity of GA-AgNPs_0.4g and GA-AgNPs_TP-1 was also assessed on the buccal mucosa fibroblast (BMF) cells using the MTT assay. The study demonstrated that antimicrobial activity of GA-AgNPs_0.4g was retained after being combined with a sub-lethal or inactive concentration of TP-1.