Diagnostic approaches of pneumonia for commercial-scale biomedical applications: An overview

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dc.contributor.authorBakare, Olalekan Olanrewaju
dc.contributor.authorFadaka, Adewale Oluwaseun
dc.contributor.authorKlein, Ashwil
dc.date.accessioned2020-12-10T10:34:23Z
dc.date.available2020-12-10T10:34:23Z
dc.date.issued2020
dc.description.abstractPneumonia remains the leading infectious cause of death among children under five years of age, and the elderly. Several biomarkers, which have been identified for its diagnosis lack specificity, as they could not differentiate viral from bacterial pathogens of the disease; these biomarkers also fail to establish a distinction between pneumonia and other associated diseases such as pulmonary tuberculosis and Human Immunodeficiency Virus (HIV). This review outlined the menace of pneumonia disease from the statistical prevalence, clinical and immunological view, challenges with the methods used in diagnosis, and more useful information about methods of diagnosis of pneumonia with their limitations as well. Additionally, the use of aptamers and antimicrobial peptides (AMPs) rather than antibodies to bind and recognize receptors for diagnostics, offers several advantages over other biomarkers shortcomings such as non-specificity.en_US
dc.identifier.citationBakare, O. O. et al. (2020). Diagnostic approaches of pneumonia for commercial-scale biomedical applications: An overview. All Life ,13(1), 532-547en_US
dc.identifier.issn2689-5307
dc.identifier.urihttps://doi.org/10.1080/26895293.2020.1826363
dc.identifier.urihttp://hdl.handle.net/10566/5494
dc.language.isoenen_US
dc.publisherTaylor & Francisen_US
dc.subjectPneumoniaen_US
dc.subjectAptamersen_US
dc.subjectAntimicrobial peptidesen_US
dc.subjectBiomarkersen_US
dc.subjectBioinformaticsen_US
dc.titleDiagnostic approaches of pneumonia for commercial-scale biomedical applications: An overviewen_US
dc.typeArticleen_US

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