Clinically relevant metallic nanoparticles in tuberculosis diagnosis and therapy

Simple item page
dc.contributor.authorAkinnawo, Christianah Aarinola
dc.contributor.authorDube, Admire
dc.date.accessioned2024-09-16T10:55:59Z
dc.date.available2024-09-16T10:55:59Z
dc.date.issued2024
dc.description.abstractGlobally a significant burden of tuberculosis (TB) is faced, which is difficult to eradicate due to patients' non-adherence, and drug-resistant strains that are spreading at an alarming rate. Novel approaches are required to improve diagnosis and treatment. Metallic nanoparticles (MNPs) have demonstrated potential as sensor probes and in combination therapy, which combines MNPs with antimycobacterial drugs to develop new treatment and theranostic approaches. To strengthen the theoretical foundation toward the clinical application of TB nanomedicine, this review focuses on the properties and effectiveness of therapeutically relevant MNPs. It also elaborates on their antimycobacterial mechanisms. This review aims to analyze the body of literature on the topic, pinpoint important empirical findings, and identify knowledge gaps that can provide a basis for future research endeavors and translation of the technologies. Current data suggest that MNPs are potential systems for efficient diagnosis and treatment although additional pre-clinical and clinical research is needed to bring these technologies to the clinic.
dc.identifier.citationAkinnawo, C.A. and Dube, A., 2024. Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy. Advanced Therapeutics, p.2400189.
dc.identifier.issn23663987
dc.identifier.urihttps://doi.org/10.1002/adtp.202400189
dc.identifier.urihttps://hdl.handle.net/10566/16156
dc.language.isoen
dc.publisherJohn Wiley and Sons Inc
dc.subjectAntimycobacterial treatments
dc.subjectMetal nanocomposites
dc.subjectMetal nanoparticles
dc.subjectMetal oxide nanoparticles
dc.subjectTB diagnosis
dc.titleClinically relevant metallic nanoparticles in tuberculosis diagnosis and therapy
dc.typeArticle

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
aarinola_clinically relevant metallic nanoparticles_2024.pdf
Size:
872.34 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Research Articles (School of Pharmacy)