The search for the ideal biocatalyst

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Date

2002

Journal Title

Journal ISSN

Volume Title

Publisher

Nature Publishing Group

Abstract

While the use of enzymes as biocatalysts to assist in the industrial manufacture of fine chemicals and pharmaceuticals has enormous potential, application is frequently limited by evolution-led catalyst traits. The advent of designer biocatalysts, produced by informed selection and mutation through recombinant DNA technology, enables production of process-compatible enzymes. However, to fully realize the potential of designer enzymes in industrial applications, it will be necessary to tailor catalyst properties so that they are optimal not only for a given reaction but also in the context of the industrial process in which the enzyme is applied.

Description

Keywords

Catalyst, Enzymes as biocatalysts, Designer biocatalysts, Process-compatible enzymes

Citation

Burton, S., Cowan, D.A., Woodley, J.M. (2002). The search for the ideal biocatalyst. Nature Biotechnology, 20:35-46.