Association among sperm chromatin condensation, sperm DNA fragmentation and 8-OHdG in seminal plasma and semen parameters in infertile men with oligoasthenoteratozoospermia

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dc.contributor.authorHologlu, D
dc.contributor.authorGunes, S
dc.contributor.authorHenkel, R
dc.date.accessioned2022-08-04T20:53:36Z
dc.date.available2022-08-04T20:53:36Z
dc.date.issued2021
dc.description.abstractThe present study aimed to investigate the clinical role of standard sperm diagnosis parameters (sperm concentration, motility, morphology) as well as aniline blue staining of histones, 8-OHdG, TUNEL assay were performed on semen samples in infertile men with oligoasthenoteratozoospermia (OAT). Thirty-two infertile and ten proven fertile men were included in the study. Chromatin condensation sperm in infertile men was significantly lower compared to the fertile men (p < 0.0001). Age, sperm concentration, morphology and motility were significantly negatively correlated with chromatin condensation (p < 0.05). However, no significant correlations among the chromatin condensation, SDF and sperm DNA damage were detected in terms of 8- OHdG concentration.en_US
dc.identifier.citationHologlu, Dilara et al. “Association Among Sperm Chromatin Condensation, Sperm DNA Fragmentation and 8‐OHdG in Seminal Plasma and Semen Parameters in Infertile Men with Oligoasthenoteratozoospermia.” Andrologia 54.1 (2022): e14268–n/a. Web.en_US
dc.identifier.issn0303-4569
dc.identifier.uriDOI: 10.1111/and.14268
dc.identifier.urihttp://hdl.handle.net/10566/7698
dc.language.isoenen_US
dc.publisherWileyen_US
dc.subject8-OHdGen_US
dc.subjectchromatin condensationen_US
dc.subjectOATen_US
dc.subjectsemen parametersen_US
dc.subjectsperm DNA fragmentationen_US
dc.titleAssociation among sperm chromatin condensation, sperm DNA fragmentation and 8-OHdG in seminal plasma and semen parameters in infertile men with oligoasthenoteratozoospermiaen_US
dc.typeArticleen_US

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