Concept Based Knowledge Discovery From Biomedical Literature

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dc.contributor.advisorBajic, Vladimir
dc.contributor.authorRadovanovic, Aleksandar
dc.date.accessioned2022-03-09T07:57:04Z
dc.date.accessioned2024-05-17T07:58:00Z
dc.date.available2022-03-09T07:57:04Z
dc.date.available2024-05-17T07:58:00Z
dc.date.issued2009
dc.descriptionPhilosophiae Doctor - PhDen_US
dc.description.abstractAdvancement in biomedical research and continuous growth of scientific literature available in electronic form, calls for innovative methods and tools for information management, knowledge discovery, and data integration. Many biomedical fields such as genomics, proteomics, metabolomics, genetics, and emerging disciplines like systems biology and conceptual biology require synergy between experimental, computational, data mining and text mining technologies. A large amount of biomedical information available in various repositories, such as the US National Library of Medicine Bibliographic Database, emerge as a potential source of textual data for knowledge discovery. Text mining and its application of natural language processing and machine learning technologies to problems of knowledge discovery, is one of the most challenging fields in bioinformatics. This thesis describes and introduces novel methods for knowledge discovery and presents a software system that is able to extract information from biomedical literature, review interesting connections between various biomedical concepts and in so doing, generates new hypotheses. The experimental results obtained by using methods described in this thesis, are compared to currently published results obtained by other methods and a number of case studies are described. This thesis shows how the technology presented can be integrated with the researchers' own knowledge, experimentation and observations for optimal progression of scientific research.en_US
dc.identifier.urihttps://hdl.handle.net/10566/15293
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectBioinformatiesen_US
dc.subjectText miningen_US
dc.subjectPubMeden_US
dc.subjectEntity recognitionen_US
dc.subjectInformation extractionen_US
dc.subjectRelation Extractionen_US
dc.subjectLevenshtein distanceen_US
dc.subjectSupervised classificationen_US
dc.subjectNatural Language Processingen_US
dc.subjectMachine learningen_US
dc.titleConcept Based Knowledge Discovery From Biomedical Literatureen_US

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Philosophiae Doctor - PhD (Bioinformatics)