Oral colonization of Gram-negative anaerobes as a risk factor for preterm birth
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Date
2011
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Landes Bioscience
Abstract
Preterm birth significantly impacts on neonatal
morbidity and mortality and is apparently increasing worldwide.
Several studies have attempted to define a causative role
for periodontal disease in adverse pregnancy outcomes but
few have focused on the microbiology of periodontal disease
in relation to these outcomes.
Results: The evidence for a positive correlation is strong,
supported by microbiological and immunological findings.
Conflicting results are often associated with uncontrolled confounding
factors.
Materials and Methods: A literature search was conducted
in order to establish whether or not a role exists for oral Gramnegative
bacteria in adverse pregnancy outcomes. Association
and intervention studies are summarized along with pathogenic
potential of the Gram-negative bacteria most frequently
implicated in periodontal disease.
Description
Keywords
Periodontal disease, Red complex, Orange complex, Preterm birth
Citation
Africa, C.W.J. (2011). Oral colonization of Gram-negative anaerobes as a risk factor for preterm birth. Virulence, 2(6): 498-508