Intralesional autogenous fat injection in oral submucous fibrosis

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dc.contributor.advisorMorkel, Jean A
dc.contributor.authorGounden, Tashen
dc.date.accessioned2022-02-09T09:16:54Z
dc.date.accessioned2024-06-04T07:57:22Z
dc.date.available2022-02-09T09:16:54Z
dc.date.available2024-06-04T07:57:22Z
dc.date.issued2021
dc.descriptionMagister Chirurgiae Dentium (MChD)en_US
dc.description.abstractOral submucous fibrosis (OSMF) is a chronic disorder characterized by the fibrosis of the mucosal lining of the upper digestive tract involving the oral cavity, oropharynx, hypopharynx and the upper third of the oesophagus. Areca nut chewing has been implicated in the aetiology of this condition. This condition is prevalent in Kwa-Zulu Natal (KZN), South Africa, with many patients suffering from varying degrees of severity of this disease. At Inkosi Albert Luthuli Central Hospital autogenous fat injections into the fibrous bands are being used as a means of treating OSMF. Anecdotal evidence suggested that this type of treatment modality helps to relieve the symptoms experienced by patients. There is no scientific data supporting this claim. The aim of the study was to establish the effectiveness of intralesional autogenous fat injections in patients with oral submucous fibrosis. The objectives of this study was to record the demographic details and medical information of the patients, evaluate the inter-incisal mouth opening, to assess the presence or absence of restricted tongue movements, record pain of the patients and record quality of life via a condition specific questionnaire prior to treatment and at six months post operativelyen_US
dc.identifier.urihttps://hdl.handle.net/10566/15787
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.rights.holderUniversity of the Western Capeen_US
dc.subjectOral submucous fibrosisen_US
dc.subjectOral potentially malignant disorderen_US
dc.subjectAutogenous fat graftingen_US
dc.subjectFat injectionen_US
dc.subjectLipoaspirateen_US
dc.subjectAdipose derived stem cellsen_US
dc.titleIntralesional autogenous fat injection in oral submucous fibrosisen_US

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