Antinociceptive, anti-inflammatory and antipyretic activities of the leaf methanol extract of ruta graveolens l. (rutaceae) in mice and rats
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Date
2014
Journal Title
Journal ISSN
Volume Title
Publisher
African Networks Ethnomedicines
Abstract
Ruta graveolens has been used to treat toothache, earache, rheumatism and fever with little scientific evidence corroborating these uses. The leaf methanol extract of Ruta graveolens was evaluated for antinociceptive activity using the acetic acid writhing and hot-plate tests in mice, also anti-inflammatory and antipyretic activities using the carrageenan-induced oedema and E. coli-induced pyrexia tests in rats, respectively.
Description
Keywords
Antipyretic, Pharmacology, Ruta graveolens, Rutaceae
Citation
Loonat, F., & Amabeoku, G. J. (2014). Antinociceptive, anti-inflammatory and antipyretic activities of the leaf methanol extract of ruta graveolens l. (rutaceae) in mice and rats. African Journal of Traditional, Complementary and Alternative Medicines, 11 (3) , pp.173-181. 10.4314/ajtcam.v11i3.25