International Glossina Genome Initiative 2004-2014: a driver for post-genomic era research on the African continent

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dc.contributor.authorChristoffels, Alan
dc.contributor.authorMasiga, Daniel K.
dc.contributor.authorBerriman, Matthew
dc.contributor.authorLehane, Mike
dc.contributor.authorToure', Yeya
dc.contributor.authorAksoy, Serap
dc.date.accessioned2015-06-09T14:29:36Z
dc.date.available2015-06-09T14:29:36Z
dc.date.issued2014
dc.description.abstractHuman African trypanosomiasis (HAT), also known as sleeping sickness, is a neglected disease that impacts 70 million people distributed over 1.55 million km2 in sub- Saharan Africa and includes at least 50% of the population of theDemocratic Republic of the Congo [1]. Trypanosoma brucei gambiense accounts for more than 98% of the infections in central and West Africa, the remaining infections being from Trypanosoma brucei rhodesiense in East Africa [2]. The parasites are transmitted to the hosts through the bite of an infected tsetse fly. Disease control is challenging as there are no vaccines, and effective, easily delivered drugs are still lacking. Treatment invariably involves lengthy hospitalization, with both medical and socioeconomic consequences.en_US
dc.description.accreditationWeb of Science
dc.identifier.citationChristoffels, A., et al. (2014). International Glossina Genome Initiative 2004–2014: a driver for post-genomic era research on the African continent. PLoS Neglected Tropical Diseases, 8(8): e3024. doi:10.1371/journal.pntd.0003024en_US
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/10566/1498
dc.language.isoenen_US
dc.privacy.showsubmitterfalse
dc.publisherPLOS
dc.rights© 2014 Christoffels et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.source.urihttp://dx.doi.org/10.1371/journal.pntd.0003024
dc.status.ispeerreviewedtrue
dc.subjectHuman African trypanosomiasis (HAT)
dc.subjectSleeping sickness
dc.subjectSub-Saharan Africa
dc.subjectDemocratic Republic of the Congo
dc.subjectWorld Health Organization Tropical Diseases Research (WHOTDR)
dc.titleInternational Glossina Genome Initiative 2004-2014: a driver for post-genomic era research on the African continenten_US
dc.typeArticleen_US

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